Direct arene trifluoromethylation enabled by promiscuous activity of fungal laccase

Laccase from Trametes versicolor was found to oxidize non-phenolic arenes and enable the trifluoromethylation of arenes in the presence of in situ generated CF 3 radicals at a catalyst loading as low as 0.0034%. The biocatalytic trifluoromethylation proceeded under mild conditions and could increase...

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Veröffentlicht in:	Organic & biomolecular chemistry 2023-11, Vol.21 (45), p.8975-8978
Hauptverfasser:	Goh, Yi Ling, Long, Shi Yang Preston, Wong, Mun Fei Eddy, Tan, Lee Ling, Tiong, Elaine, Wong, Fong Tian, Liu, Zhennan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds Catalysts Laccase Organic chemistry Phenolic compounds Phenols
Online-Zugang:	Volltext
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