Ovarian follicle transcriptome dynamics reveals enrichment of immune system process during transition from small to large follicles in cyclic Indian Ghoongroo pigs

Ovarian follicle transcriptome dynamics reveals enrichment of immune system process during transition from small to large follicles in cyclic Indian Ghoongroo pigs

Ovarian follicular development is a critical determinant of reproductive performance in litter bearing species like pigs, wherein economic gains depend on litter size. The study aimed to gain insight into the differentially expressed genes (DEGs) and signalling pathways regulating follicular growth...

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Veröffentlicht in:Journal of reproductive immunology 2023-12, Vol.160, p.104164-104164, Article 104164
Hauptverfasser: Bharati, Jaya, Kumar, Satish, Mohan, N.H., Chandra Das, Bikash, Devi, Salam Jayachitra, Gupta, Vivek Kumar
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Estrous
Female
Gene Expression Profiling
Granulosa
Granulosa Cells - metabolism
Growth
Immune
Immune System Phenomena
Ovarian Follicle
Signalling
Steroidogenesis
Swine
Transcriptome
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Zusammenfassung:Ovarian follicular development is a critical determinant of reproductive performance in litter bearing species like pigs, wherein economic gains depend on litter size. The study aimed to gain insight into the differentially expressed genes (DEGs) and signalling pathways regulating follicular growth and maturation in Ghoongroo pigs. Transcriptome profiling of porcine small follicles (SF) and large follicles (LF) was conducted using NovaSeq600 sequencing platform and DEGs were identified using DESeq2 with threshold of Padj
ISSN:0165-0378
1872-7603
DOI:10.1016/j.jri.2023.104164