Conducting organic Langmuir–Blodgett films as chemical sensors

A glucose sensor was designed by immobilizing glucose oxidase (GOD) in a conducting organic Langmuir–Blodgett film (LB). GOD–LB complexes were characterized by infrared absorption. The rate of change in the dc conductivity for GOD–LB complexes is ranging from −13.4 to 7.9% after immersion in 3 × 10...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2005-07, Vol.108 (1), p.404-408
Hauptverfasser:	Watanabe, Nobuaki, Ohnuki, Hitoshi, Saiki, Takafumi, Endo, Hideaki, Izumi, Mitsuru, Imakubo, Tatsuro
Format:	Artikel
Sprache:	eng
Schlagworte:	Actuators BEDO-TTF Biochemistry Conduction Glucose Glucose oxidase Infrared absorption Infrared and Raman spectroscopy Langmuir-Blodgett films Langmuir–Blodgett techniques Organic conductors based on radical and/or anion salts Platforms Semiconducting films Sensors
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Beschreibung
Zusammenfassung:	A glucose sensor was designed by immobilizing glucose oxidase (GOD) in a conducting organic Langmuir–Blodgett film (LB). GOD–LB complexes were characterized by infrared absorption. The rate of change in the dc conductivity for GOD–LB complexes is ranging from −13.4 to 7.9% after immersion in 3 × 10 −2 mol/l glucose for 2 min. GOD possibly absorbs in the LB films and maintains its bioactivity and sensitivity. The present technique with highly ordered conducting LB films is to be used as a suitable platform for immobilization of the enzyme for sensor architecture.
ISSN:	0925-4005 1873-3077
DOI:	10.1016/j.snb.2005.01.048