Synthesis of Isoquinolines and Related Heterocycles under Visible-Light Conditions

Visible-light catalysis is now widely acknowledged as a potent approach for efficiently constructing various types of frameworks, particularly bioactive compounds, with high yields. However, there is still a strong need for further advancements in these methods because certain delicate compounds can...

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Veröffentlicht in:Journal of organic chemistry 2023-11, Vol.88 (22), p.15750-15760
Hauptverfasser: Yuan, Yurong, Faure, Clara, Menigaux, Doriane, Berthelot, Mathieu, Belmont, Philippe, Brachet, Etienne
Format: Artikel
Sprache:eng
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Zusammenfassung:Visible-light catalysis is now widely acknowledged as a potent approach for efficiently constructing various types of frameworks, particularly bioactive compounds, with high yields. However, there is still a strong need for further advancements in these methods because certain delicate compounds cannot be synthesized due to structural sensitivity. In this context, a seamless reaction pathway toward 6-membered ring nitrogen-containing heterocycles is presented here, offering access to isoquinoline derivatives and related heterocycles.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.3c01782