GLUT2, glucose and oxygen sensing in CD8+ T cells
Glucose transporter-mediated uptake of glucose is a key metabolic checkpoint in T cells. Fu et al. have identified GLUT2 as a critical regulator of CD8 + T cell metabolism and function in response to glucose and oxygen availability.
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| Veröffentlicht in: | Nature metabolism 2023-11, Vol.5 (11), p.1850-1851 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Glucose transporter-mediated uptake of glucose is a key metabolic checkpoint in T cells. Fu et al. have identified GLUT2 as a critical regulator of CD8
+
T cell metabolism and function in response to glucose and oxygen availability. |
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| ISSN: | 2522-5812 2522-5812 |
| DOI: | 10.1038/s42255-023-00914-8 |