Cytological findings of phosphaturic mesenchymal tumor: Report of a case with summary of prior published cases

Phosphaturic mesenchymal tumor (PMT) is a rare neoplasm causing tumor‐induced osteomalacia (TIO) and is characterized by secretion of FGF23, renal phosphate wasting and hypophosphataemia. It can be completely cured by resection and therefore its diagnosis is of utmost importance. Although the histol...

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Veröffentlicht in:Diagnostic cytopathology 2024-02, Vol.52 (2), p.E44-E47
Hauptverfasser: Das, Oindrila, Mohin, Md, Dey, Soumya, Kar, Anish, Singhania, Pankaj, Adhikari, Souvik, Chowdhury, Subhankar, Chatterjee, Uttara
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Sprache:eng
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Zusammenfassung:Phosphaturic mesenchymal tumor (PMT) is a rare neoplasm causing tumor‐induced osteomalacia (TIO) and is characterized by secretion of FGF23, renal phosphate wasting and hypophosphataemia. It can be completely cured by resection and therefore its diagnosis is of utmost importance. Although the histology is well described, there is sparse literature on cytology of PMT and only three cases have been described so far. A 45‐year‐old lady presented with a non‐tender mass in hard palate for 2 years from which fine‐needle aspiration was done. The smears were paucicellular and showed bland spindle cells embedded in osteoid‐like stromal matrix in a hemorrhagic background. Here we take the opportunity to describe the cytological findings of PMT along with its cytological differentials and a summary of prior published cases.
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.25245