Right–Left Ventricular Interdependence in Repaired Tetralogy of Fallot Patients With Right Ventricular Heart Failure

Background Patients with repaired tetralogy of Fallot (rTOF) continue to face a heightened risk of deteriorating cardiac function, and quantitative techniques of cardiac MRI‐derived cardiac structure and function provide an opportunity to explore the causes and mechanisms of cardiac deterioration. P...

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Veröffentlicht in:Journal of magnetic resonance imaging 2024-08, Vol.60 (2), p.628-639
Hauptverfasser: Jiang, Li, Li, Yuan, Huang, Shan, Han, Pei‐Lun, Yan, Wei‐Feng, Fang, Han, Yang, Zhi‐Gang
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Sprache:eng
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Zusammenfassung:Background Patients with repaired tetralogy of Fallot (rTOF) continue to face a heightened risk of deteriorating cardiac function, and quantitative techniques of cardiac MRI‐derived cardiac structure and function provide an opportunity to explore the causes and mechanisms of cardiac deterioration. Purpose To explore right–left ventricular interdependence in rTOF patients before and after the onset of right ventricular (RV) heart failure. Study Type Retrospective. Population One hundred eighteen rTOF patients (21.85 [16.74, 29.20] years, 58 females) and 34 controls (23.5 [21, 26.5] years, 17 females) that underwent cardiac MRI were analyzed, with rTOF patients being further subdivided into those with preserved RV function (N = 54) and those that experienced RV heart failure (N = 64). Field Strength/Sequence 3.0 T/balanced steady‐state free precession sequence. Assessment RV, left ventricular (LV), and septal strain; RV and LV volume. Statistical Tests Chi‐squared tests or Fisher's exact test, One‐way ANOVAs with Bonferroni's post hoc test, Pearson/Spearman correlation, and multivariate backward linear regression analysis. A two‐tailed P 
ISSN:1053-1807
1522-2586
1522-2586
DOI:10.1002/jmri.29080