Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC. on SH-SY5Y based on ROS mediated mitochondrial apoptosis pathway

Zanthoxylum armatum DC. (ZADC) is a traditional medicinal plant with various pharmacological activities and is widely used in China, Japan, India, and other regions. Previous studies have revealed that the methanol extract of ZADC can cause neurotoxicity symptoms in rats, such as drooling, decreased...

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Veröffentlicht in:	Journal of ethnopharmacology 2024-01, Vol.319 (Pt 3), p.117321-117321, Article 117321
Hauptverfasser:	Guo, Jiafu, Yang, Nannan, Zhang, Jian, Huang, Yan, Xiang, Qiwen, Wen, Jiayu, Chen, Yan, Hu, Tingting, Qiuyan, Liu, Rao, Chaolong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate Animals Apoptosis bcl-2-Associated X Protein Caspase 3 Caspase 9 Chromatography, Liquid Component analysis Humans Methanol Mitochondria Mitochondrion Neuroblastoma Rats Reactive Oxygen Species ROS SH-SY5Y Superoxide Dismutase Tandem Mass Spectrometry Zanthoxylum Zanthoxylum armatum DC
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