Analysis of General Toxicity of Ergoferon

For antibody-based drugs, it is important and relevant to study their toxic effects, which can often become limiting when prescribing this type of therapy. General toxicity of antiviral drug Ergoferon based on technologically processed antibodies was studied on sexually mature animals. Analysis of a...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2023-09, Vol.175 (5), p.644-648
Hauptverfasser: Danchenko, E. A., Ertuzun, I. A., Bugaeva, L. I., Lebedeva, S. A., Denisova, T. D., Lavrova, E. B., Korzhova, T. M., Tarasov, S. A.
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Sprache:eng
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Zusammenfassung:For antibody-based drugs, it is important and relevant to study their toxic effects, which can often become limiting when prescribing this type of therapy. General toxicity of antiviral drug Ergoferon based on technologically processed antibodies was studied on sexually mature animals. Analysis of acute toxicity showed the absence of lethal outcomes when the drug was administered to adult rats at the maximum tolerated doses. In a study of repeated dose toxicity, no adverse effects of the drug were detected.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-023-05918-8