Biventricular Dysfunction and Ventricular Interdependence in Patients With Pulmonary Hypertension: A 3.0‐T Cardiac MRI Feature Tracking Study

Background Pulmonary hypertension (PH) results in right ventricular (RV) dysfunction, subsequently leading to left ventricular (LV) impairment. The mechanism underlying ventricular interdependence is largely uninvestigated. Purpose To explore the biventricular dysfunction and the ventricular interde...

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Veröffentlicht in:Journal of magnetic resonance imaging 2024-07, Vol.60 (1), p.350-362
Hauptverfasser: Fang, Han, Wang, Jin, Shi, Rui, Li, Yuan, Li, Xue‐Ming, Gao, Yue, Shen, Li‐Ting, Qian, Wen‐Lei, Jiang, Li, Yang, Zhi‐Gang
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Sprache:eng
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Zusammenfassung:Background Pulmonary hypertension (PH) results in right ventricular (RV) dysfunction, subsequently leading to left ventricular (LV) impairment. The mechanism underlying ventricular interdependence is largely uninvestigated. Purpose To explore the biventricular dysfunction and the ventricular interdependence in PH patients. Study Type Retrospective. Population One hundred and seven PH patients (mean pulmonary artery pressure >20 mmHg) and 72 age‐ and sex‐matched controls with cardiac magnetic resonance imaging (MRI) studies. Field Strength/Sequence 3.0 T/balanced steady‐state free precession sequence. Assessment LV and RV ejection fractions (EF) and RV and LV radial, circumferential, and longitudinal strains were assessed using commercial software. Strains were compared between controls, PH patients with preserved RVEF (RVEF ≥40%, N = 48), and PH patients with reduced RVEF (RVEF
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.29044