Associations of presenting visual acuity with morphological changes on OCT in neovascular age-related macular degeneration: PRECISE Study Report 2

Purpose To study associations of optical coherence tomography (OCT) features with presenting visual acuity (VA) in treatment naive neovascular age-related macular degeneration (nAMD). Methods Patients with nAMD initiated on aflibercept therapy were recruited from December 2019 to August 2021. Demogr...

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Veröffentlicht in:	Eye (London) 2024-03, Vol.38 (4), p.757-765
Hauptverfasser:	Chandra, Shruti, Gurudas, Sarega, Burton, Benjamin J. L., Menon, Geeta, Pearce, Ian, Mckibbin, Martin, Kotagiri, Ajay, Talks, James, Grabowska, Anna, Ghanchi, Faruque, Gale, Richard, Giani, Andrea, Chong, Victor, Yamaguchi, Taffeta Ching Ning, Pal, Bishwanath, Thottarath, Sridevi, Pakeer, Raheeba Muhamed, Chandak, Swati, Montesel, Andrea, Sivaprasad, Sobha
Format:	Artikel
Sprache:	eng
Schlagworte:	692/53/2423 706/703 Acuity Age Aged Angiogenesis Inhibitors - therapeutic use Atrophy Eye Female Fibrosis Fluorescein Angiography Humans Intravitreal Injections Laboratory Medicine Macular degeneration Macular Degeneration - drug therapy Male Medicine Medicine & Public Health Ophthalmology Pharmaceutical Sciences/Technology Ranibizumab Retina Surgery Surgical Oncology Tomography, Optical Coherence Vascular diseases Visual Acuity Wet Macular Degeneration - diagnosis Wet Macular Degeneration - drug therapy
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Zusammenfassung:	Purpose To study associations of optical coherence tomography (OCT) features with presenting visual acuity (VA) in treatment naive neovascular age-related macular degeneration (nAMD). Methods Patients with nAMD initiated on aflibercept therapy were recruited from December 2019 to August 2021. Demographic and OCT (Spectralis, Heidelberg Engineering) features associated with good VA (VA ≥ 68 ETDRS letters, Snellen ≥ 6/12) and poor VA (VA
ISSN:	0950-222X 1476-5454
DOI:	10.1038/s41433-023-02769-5