Prophylactic use of cardiac medications for delay of left ventricular dysfunction in Duchenne muscular dystrophy

Prophylactic use of cardiac medications for delay of left ventricular dysfunction in Duchenne muscular dystrophy

Background Epidemiological support for prophylactic treatment of left ventricular dysfunction (LVD) in Duchenne muscular dystrophy is limited. We used retrospective, population‐based surveillance data from the Muscular Dystrophy Surveillance, Tracking and Research Network to evaluate whether prophyl...

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Veröffentlicht in:Birth defects research 2024-01, Vol.116 (1), p.e2260-n/a
Hauptverfasser: Conway, Kristin M., Thomas, Shiny, Ciafaloni, Emma, Khan, Rabia S., Mann, Joshua R., Romitti, Paul A., Mathews, Katherine D.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adrenal Cortex Hormones - therapeutic use
cardiomyopathy
cardioprotective
Corticoids
corticosteroid
Corticosteroids
Disease prevention
Duchenne muscular dystrophy
Duchenne's muscular dystrophy
Dystrophy
Echocardiography
Epidemiology
Heart
Humans
Male
Muscular dystrophy
Muscular Dystrophy, Duchenne - complications
Muscular Dystrophy, Duchenne - drug therapy
Prophylaxis
Retrospective Studies
Steroids
Surveillance
Ventricle
Ventricular Dysfunction, Left - complications
Ventricular Dysfunction, Left - drug therapy
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Zusammenfassung:Background Epidemiological support for prophylactic treatment of left ventricular dysfunction (LVD) in Duchenne muscular dystrophy is limited. We used retrospective, population‐based surveillance data from the Muscular Dystrophy Surveillance, Tracking and Research Network to evaluate whether prophylaxis delays LVD onset. Methods We analyzed 455 males born during 1982–2009. Age at first abnormal echocardiogram (ejection fraction
ISSN:2472-1727
2472-1727
DOI:10.1002/bdr2.2260