Transoral robotic surgery in HPV+ oropharyngeal cancer of unknown primary

Transoral robotic surgery in HPV+ oropharyngeal cancer of unknown primary

This study was designed to assess trends in and outcomes associated with TORS-treated HNCUP using a large national database. HPV+ oropharyngeal HNCUPs were isolated from the 2004–2017 National Cancer Database. Overall survival (OS) was assessed, with patients stratified by 1) use of TORS and 2) whet...

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Veröffentlicht in:American journal of otolaryngology 2024-01, Vol.45 (1), p.104060-104060, Article 104060
Hauptverfasser: Roman, Kelsey M., Nguyen, Cecilia, Torabi, Sina J., Berger, Michael H., Kuan, Edward C., Tjoa, Tjoson, Haidar, Yarah M.
Format: Artikel
Sprache:eng
Schlagworte:
Head and neck cancer
Human papillomavirus
Oropharyngeal cancer
Transoral robotic surgery
Unknown primary
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Zusammenfassung:This study was designed to assess trends in and outcomes associated with TORS-treated HNCUP using a large national database. HPV+ oropharyngeal HNCUPs were isolated from the 2004–2017 National Cancer Database. Overall survival (OS) was assessed, with patients stratified by 1) use of TORS and 2) whether the occult tumor was ultimately located. Demographic and oncologic predictors of survival were evaluated on regression. The cohort contained 284,734 cases, of which 8336 were HNCUPs. HNCUPs represented 2.49 % of all HNSCC in 2010 versus 3.13 % in 2017. 3897 (46.7 %) of these unknown primaries were ultimately identified. The proportion of cases treated with TORS increased from 6.9 % in 2010 to 18.1 % in 2017 (p 
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2023.104060