Decolonization in Nursing Homes to Prevent Infection and Hospitalization

Nursing home residents are often colonized with antibiotic-resistant bacteria. In this trial involving 28 nursing homes, decolonization with chlorhexidine and povidone–iodine reduced the risk of hospitalization for infection.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2023-11, Vol.389 (19), p.1766-1777
Hauptverfasser:	Miller, Loren G., McKinnell, James A., Singh, Raveena D., Gussin, Gabrielle M., Kleinman, Ken, Saavedra, Raheeb, Mendez, Job, Catuna, Tabitha D., Felix, James, Chang, Justin, Heim, Lauren, Franco, Ryan, Tjoa, Thomas, Stone, Nimalie D., Steinberg, Karl, Beecham, Nancy, Montgomery, Jocelyn, Walters, DeAnn, Park, Steven, Tam, Steven, Gohil, Shruti K., Robinson, Philip A., Estevez, Marlene, Lewis, Brian, Shimabukuro, Julie A., Tchakalian, Gregory, Miner, Aaron, Torres, Crystal, Evans, Kaye D., Bittencourt, Cassiana E., He, Jiayi, Lee, Eunjung, Nedelcu, Christine, Lu, Julia, Agrawal, Shalini, Sturdevant, S. Gwynn, Peterson, Ellena, Huang, Susan S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Administration, Intranasal Aging Aging General Anti-Infective Agents, Local - administration & dosage Anti-Infective Agents, Local - therapeutic use Asymptomatic Infections - therapy Bacterial Infections Baths Chlorhexidine Chlorhexidine - administration & dosage Chlorhexidine - therapeutic use Clinical Medicine Cross Infection - epidemiology Cross Infection - prevention & control Cross Infection - therapy Geriatrics Hospital-Based Clinical Medicine Hospitalization Hospitalization - statistics & numerical data Humans Infectious Disease Infectious Disease General Iodine Medical equipment Multidrug resistance Multidrug resistant organisms Nursing care Nursing homes Nursing Homes - statistics & numerical data Patient Transfer - statistics & numerical data Polyvinylpyrrolidone Povidone Povidone-Iodine - administration & dosage Povidone-Iodine - therapeutic use Prevention Skin Care - methods Staphylococcus infections Statistical analysis
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Beschreibung
Zusammenfassung:	Nursing home residents are often colonized with antibiotic-resistant bacteria. In this trial involving 28 nursing homes, decolonization with chlorhexidine and povidone–iodine reduced the risk of hospitalization for infection.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2215254