MICROBIOLOGICAL FEATURES OF A LAPAROTOMY WOUND COMPLICATED BY POSTOPERATIVE EVENTRATION AGAINST THE BACKGROUND OF AN ONCOLOGICAL PROCESS

This article presents the results of a study of the qualitative and quantitative microflora content of the wound exudate of a laparotomy wound complicated by eventration in patients with malignant neoplasms of the abdominal cavity. This study aimed to investigate the peculiarities of the qualitative and quantitative composition of the laparotomy wound microflora in cancer patients with postoperative eventation. After all, postoperative event is always accompanied by the occurrence of purulent-septic complications from the laparotomy wound. These microbiological features should be taken into account in order to timely prevent or treat postoperative event in cancer patients, that is, in the appointment of antimicrobial therapy, features of purulent wound treatment, etc. We studied 34 patients with surgical diseases of the abdominal cavity with postoperative eventration. We studied the species content of microorganisms, their population level, the index of constancy, the frequency of species detection, the index of significance, and the index of quantitative dominance. The microbiological spectrum of laparotomy wound exudate, in case of postoperative eventration in patients with malignant neoplasms of the abdominal cavity, is characterized by a probable predominance of the number of cultivated strains of the genus Proteus, Pseudomonas aeruginosa, the appearance of yeast-like fungi of the genus Candida and the absence of S. aureus growth in the early stages. There was an increase in the population level of E. coli, Pseudomonas aeruginosa, and microorganisms of the genus Proteus, with a prevalence of the latter compared to non-cancer patients, and a lower number of Staphylococcus aureus colonies. The dominant microorganisms of wound exudate are E. coli and Enterococcus faecalis; in patients with malignant abdominal neoplasms, the highest coefficient of quantitative dominance is observed in microorganisms of the genus Proteus. The presence of secondary immunodeficiency, cachexia, anaemia, etc. in patients with malignant neoplasms of the abdominal cavity causes a 'sluggish' purulent-inflammatory process in the laparotomy wound area in the event of postoperative eventration.