An engineered nanoplatform cascade to relieve extracellular acidity and enhance resistance-free chemotherapy

Tumor extracellular acidity and chemoresistance are regarded as the main obstacles to achieving optimal chemotherapeutic efficacy in tumor therapy. Herein, a new kind of acid-cascade P-S-Z nanoparticles (NPs) is developed to relieve extracellular acidosis and enhance chemotherapy without causing dru...

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Veröffentlicht in:	Journal of controlled release 2023-11, Vol.363, p.562-573
Hauptverfasser:	Tong, Yuqing, Gu, Meng, Luo, Xingyu, Qi, Haifeng, Jiang, Wei, Deng, Yu, Wei, Lulu, Liu, Jun, Ding, Yin, Cai, Jianfeng, Hu, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid-activated nanoparticles Acidosis Chemotherapy Lactate P53 Tumor drug resistance
Online-Zugang:	Volltext
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