Association of Clinical Signs of Chorioamnionitis with Histological Chorioamnionitis and Neonatal Outcomes in Women with Premature Rupture of Membranes

BackgroundPremature rupture of membrane (PROM), especially when preterm or prolonged is associated with an increased risk of chorioamnionitis with its attendant feto-maternal complications. AimThe study was aimed to determine the association of clinical signs of chorioamnionitis with histological chorioamnionitis and neonatal outcomes in women with PROM. Materials and MethodsEligible participants with clinical diagnosis of PROM at gestational age of ≥28 weeks managed between December 2018 and June 2019 were consecutively recruited. Their sociodemographic characteristics, obstetrics history, and evidence of clinical chorioamnionitis using the Gibb's criteria were obtained. Following delivery, chorioamnionitis was histologically confirmed. Primary outcome measure was the proportion of women with PROM and histological chorioamnionitis that were detected clinically. ResultsOf the 136 participants analyzed, 108 (79.4%) had term PROM, while 28 (20.6%) had preterm PROM (