Age- and Sex-Specific Disparities in Outcomes After Ticagrelor Versus Clopidogrel in East Asian Patients

Age- and Sex-Specific Disparities in Outcomes After Ticagrelor Versus Clopidogrel in East Asian Patients

It is unknown whether there are age- and gender-related differences in the safety and efficacy of potent P2Y12 inhibitors in East Asian populations with a different bleeding or ischemic propensity. Using data from the TICAKOREA (Ticagrelor Versus Clopidogrel in Asian/Korean Patients with ACS Intende...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The American journal of cardiology 2023-11, Vol.207, p.237-244
Hauptverfasser: Jang, Mi Hee, Kim, Ah-Ram, Kim, Taesun, Oh, Hyeon Jeong, Lee, Jeen Hwa, Lee, Yeon Jeong, Kim, Sehee, Lee, Junghoon, Kim, Ju Hyeon, Cha, Sung Joo, Kim, Tae Oh, Kang, Do-Yoon, Lee, Pil Hyung, Ahn, Jung-Min, Park, Duk-Woo, Park, Seung-Jung
Format: Artikel
Sprache:eng
Schlagworte:
Acute Coronary Syndrome - drug therapy
Acute coronary syndromes
Age
Aged
antiplatelets
Bleeding
bleeding events
Clopidogrel
Clopidogrel - therapeutic use
East Asian People
Effectiveness
Female
Gender
Hemorrhage - chemically induced
Hemorrhage - epidemiology
Humans
Ischemia
ischemic events
Male
Men
Patients
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors - therapeutic use
Purinergic P2Y Receptor Antagonists - therapeutic use
Safety
Sex differences
Stroke
Thrombosis
Ticagrelor - therapeutic use
Treatment Outcome
Women
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:It is unknown whether there are age- and gender-related differences in the safety and efficacy of potent P2Y12 inhibitors in East Asian populations with a different bleeding or ischemic propensity. Using data from the TICAKOREA (Ticagrelor Versus Clopidogrel in Asian/Korean Patients with ACS Intended for Invasive Management) trial comparing ticagrelor versus clopidogrel for 800 Korean patients with acute coronary syndrome, the safety and efficacy outcomes were compared according to age (
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2023.08.124