Predictors of non‐transplantable recurrence in hepatocellular carcinoma patients treated with frontline liver resection

Background and Aims Hepatocellular carcinoma (HCC) recurrence is common in patients treated with liver resection (LR). In this study, we aimed to evaluate the incidence and preoperative predictors of non‐transplantable recurrence in patients with single HCC ≤5 cm treated with frontline LR. Methods F...

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Veröffentlicht in:	Liver international 2023-12, Vol.43 (12), p.2762-2775
Hauptverfasser:	Pelizzaro, Filippo, Trevisani, Franco, Simeon, Vittorio, Vitale, Alessandro, Cillo, Umberto, Piscaglia, Fabio, Missale, Gabriele, Sangiovanni, Angelo, Foschi, Francesco G., Cabibbo, Giuseppe, Caturelli, Eugenio, Di Marco, Maria, Azzaroli, Francesco, Brunetto, Maurizia R., Raimondo, Giovanni, Vidili, Gianpaolo, Guarino, Maria, Gasbarrini, Antonio, Campani, Claudia, Svegliati‐Baroni, Gianluca, Giannini, Edoardo G., Mega, Andrea, Masotto, Alberto, Rapaccini, Gian Ludovico, Magalotti, Donatella, Sacco, Rodolfo, Nardone, Gerardo, Farinati, Fabio, Biselli, Maurizio, Caraceni, Paolo, Lani, Lorenzo, Rampoldi, Davide, Reggidori, Nicola, Santi, Valentina, Stefanini, Benedetta, Granito, Alessandro, Muratori, Luca, Sansone, Vito, Tovoli, Francesco, Dajti, Elton, Marasco, Giovanni, Ravaioli, Federico, Cappelli, Alberta, Golfieri, Rita, Mosconi, Cristina, Renzulli, Matteo, Pinto, Elisa, Palano, Giorgio, Kitenge, Maria Piera, Bertellini, Federica, Cela, Ester Marina, Facciorusso, Antonio, Pieri, Giulia, Torres, Maria Corina Plaz, Pasta, Andrea, Matthaeis, Nicoletta, Ponziani, Francesca Romana, Ghittoni, Giorgia, Lauria, Valentina, Pelecca, Giorgio, Chegai, Fabrizio, Raso, Armando, Bozzi, Alessio, Biasini, Elisabetta, Olivani, Andrea, Inno, Alessandro, Marchetti, Fabiana, Celsa, Ciro, Giuffrida, Paolo, Giacchetto, Carmelo Marco, Rancatore, Gabriele, Grassini, Maria Vittoria, Ciccia, Roberta, Grova, Alessandro, Salvato, Mauro, Franzè, Maria Stella, Saitta, Carlo, Arru, Marco, Sauchella, Assunta, Serra, Maria Grazia, Bevilacqua, Vittoria, Borghi, Alberto, Gardini, Andrea Casadei, Conti, Fabio, Dall’Aglio, Anna Chiara, Ercolani, Giorgio, Mirici, Federica, Marra, Fabio, Adotti, Valentina, Rosi, Martina, Coccoli, Pietro, Malerba, Antonio, Morisco, Filomena, Cossiga, Valentina, Capasso, Mario, Romagnoli, Veronica
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Fetoproteins Carcinoma, Hepatocellular Criteria hepatectomy Hepatectomy - methods Hepatocellular carcinoma Humans Liver Liver cancer Liver Neoplasms - pathology Liver Transplantation Microvasculature Neoplasm Recurrence, Local - pathology recurrence Retrospective Studies Risk factors Subgroups Survival Transplantation Tumors tumour size
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Zusammenfassung:	Background and Aims Hepatocellular carcinoma (HCC) recurrence is common in patients treated with liver resection (LR). In this study, we aimed to evaluate the incidence and preoperative predictors of non‐transplantable recurrence in patients with single HCC ≤5 cm treated with frontline LR. Methods From the Italian Liver Cancer (ITA.LI.CA) database, 512 patients receiving frontline LR for single HCC ≤5 cm were retrieved. Incidence and predictors of recurrence beyond Milan criteria (MC) and up‐to‐seven criteria were compared between patients with HCC
ISSN:	1478-3223 1478-3231
DOI:	10.1111/liv.15719