Impact of pre‐ablation left appendage flow velocities on long term recurrence of catheter ablation for paroxysmal atrial fibrillation

Background Despite undergoing a single ablation, many patients with paroxysmal atrial fibrillation (PAF) experience a gradually increasing recurrence rate. This study aims to examine the relationship between left atrial appendage emptying velocity (LAAeV) and filling velocity (LAAfV) profiles and 3‐...

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Veröffentlicht in:Pacing and clinical electrophysiology 2023-11, Vol.46 (11), p.1412-1418
Hauptverfasser: Cui, Jing, Du, Xin, He, Liu, Xia, Shi‐Jun, Tang, Ri‐Bo, Sang, Cai‐Hua, Long, De‐Yong, Dong, Jian‐Zeng, Ma, Chang‐Sheng
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Sprache:eng
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Zusammenfassung:Background Despite undergoing a single ablation, many patients with paroxysmal atrial fibrillation (PAF) experience a gradually increasing recurrence rate. This study aims to examine the relationship between left atrial appendage emptying velocity (LAAeV) and filling velocity (LAAfV) profiles and 3‐year recurrence of AF after ablation. Methods We conducted a prospective study of 658 consecutive PAF patients who underwent their first ablation between January 2018 and December 2019. We collected the clinical and echocardiographic characteristics of the patients. LAAeV and LAAfV were obtained from a transesophageal echocardiogram (TEE) before catheter ablation. Patients were followed at regular intervals to monitor for the primary outcome of AF recurrence. Results After a median follow‐up period of 35.3 months (range, 10.7–36.3), 288 patients (43.8%) experienced AF recurrence after catheter ablation. Patients who experienced AF recurrence had decreased LAAeV and LAAfV (LAAeV: 56.5 ± 21.2 vs. 59.6 ± 20.7 cm/s, p = .052; LAAfV: 47.5 ± 17.9 vs. 51.7 ± 18.2, p = .003). Kaplan–Meier analysis showed that patients in the low LAAeV (
ISSN:0147-8389
1540-8159
DOI:10.1111/pace.14828