Global Longitudinal Strain as Predictor of Inducible Ischemia in No Obstructive Coronary Artery Disease in the CIAO-ISCHEMIA study

Global longitudinal strain (GLS) is a sensitive marker for identifying subclinical myocardial dysfunction in obstructive coronary artery disease (CAD). Little is known about the relationship between GLS and ischemia in patients with myocardial ischemia and no obstructive CAD (INOCA). To investigate...

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Veröffentlicht in:	Journal of the American Society of Echocardiography 2024-01, Vol.37 (1), p.89-99
Hauptverfasser:	Davis, Esther F., Crousillat, Daniela R., Peteiro, Jesus, Lopez-Sendon, Jose, Senior, Roxy, Shapiro, Michael D., Pellikka, Patricia A., Lyubarova, Radmila, Alfakih, Khaled, Abdul-Nour, Khaled, Anthopolos, Rebecca, Xu, Yifan, Kunichoff, Dennis M., Fleg, Jerome L., Spertus, John A., Hochman, Judith, Maron, David, Picard, Michael H., Reynolds, Harmony R.
Format:	Artikel
Sprache:	eng
Schlagworte:	echocardiography INOCA ischemia no obstructive disease strain stress testing
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Zusammenfassung:	Global longitudinal strain (GLS) is a sensitive marker for identifying subclinical myocardial dysfunction in obstructive coronary artery disease (CAD). Little is known about the relationship between GLS and ischemia in patients with myocardial ischemia and no obstructive CAD (INOCA). To investigate the relationship between resting GLS and ischemia on stress echocardiography (SE) in patients with INOCA. Left ventricular GLS was calculated offline on resting SE images at enrollment (n=144) and 1-year follow-up (n=120) in the CIAO-ISCHEMIA study, which enrolled participants with moderate or severe ischemia by local SE interpretation (>3 segments with new or worsening wall motion abnormality and no obstructive (
ISSN:	0894-7317 1097-6795 1097-6795
DOI:	10.1016/j.echo.2023.09.006