Psychological variables associated with resistance to treatment with serotonin and noradrenaline reuptake inhibitors in fibromyalgia

The treatment of fibromyalgia (FM) often offers only partial pain relief. Among the most effective drugs for FM pain are serotonin and noradrenalin reuptake inhibitors (SNRI). Few studies investigated the affective temperaments and personality features in FM. Our objective was to explore the associa...

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Veröffentlicht in:Journal of psychosomatic research 2023-11, Vol.174, p.111493-111493, Article 111493
Hauptverfasser: Krupa, Anna J., Chrobak, Adrian A., Sołtys, Zbigniew, Korkosz, Mariusz, Nowakowski, Jarosław, Dudek, Dominika, Siwek, Marcin
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Sprache:eng
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Zusammenfassung:The treatment of fibromyalgia (FM) often offers only partial pain relief. Among the most effective drugs for FM pain are serotonin and noradrenalin reuptake inhibitors (SNRI). Few studies investigated the affective temperaments and personality features in FM. Our objective was to explore the associations between the affective temperaments, personality traits, schizotypy and response to SNRI treatment in FM. 60 FM patients: 30 responsive to SNRI (FM T[+]), 30 non-responsive to SNRI (FM T[−] and 30 healthy controls were recruited. Resistance to SNRI was defined as
ISSN:0022-3999
1879-1360
DOI:10.1016/j.jpsychores.2023.111493