Post-obstructive diuresis after posterior urethral valve treatment in neonates: a retrospective cohort study

Background The management of posterior urethral valve (PUV) in neonates requires close monitoring in the intensive care unit because of the risk of post-obstructive diuresis (POD). Our aim was to describe the incidence and factors associated with POD in newborns treated for PUV. Methods Retrospectiv...

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Veröffentlicht in:Pediatric nephrology (Berlin, West) West), 2024-02, Vol.39 (2), p.505-511
Hauptverfasser: Sartorius, Victor, Giuseppi, Agnès, Iacobelli, Silvia, Leroy-Terquem, Elise, Vinit, Nicolas, Heidet, Laurence, Blanc, Thomas, Stirnemann, Julien, Kermorvant-Duchemin, Elsa, Lapillonne, Alexandre
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Sprache:eng
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Zusammenfassung:Background The management of posterior urethral valve (PUV) in neonates requires close monitoring in the intensive care unit because of the risk of post-obstructive diuresis (POD). Our aim was to describe the incidence and factors associated with POD in newborns treated for PUV. Methods Retrospective analysis of the medical records of all neonates who underwent surgical intervention for PUV in our neonatal intensive care unit between January 2014 and April 2021. Results Of the 40 patients included, 15 (37.5%) had POD defined by urine output > 6 ml.kg −1 .h −1 during the first 24 h following urinary tract obstruction relief. At prenatal ultrasound examinations, oligohydramnios was more common in the group with POD than in the group without (53.3% vs. 8%, p  = 0.002). Preterm birth was more frequent in neonates with POD (66.7% vs. 8%; p  
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-023-06100-y