The effects of intrauterine device on cervico-vaginal smears with liquid-based cytology technique: A North-Eastern Anatolia region study in Turkey

Intrauterine device (IUD), is one of the most efficient methods of contraception. The aim of study to investigate the effects of intrauterine device in cervicovaginal smears with liquid based cytology technique in our patient population. Cervicovaginal smears of 5492 patients who sought the services of the pathology department in a sixmonth period were reviewed retrospectively. Samples were prepared with liquid based cytology technique. The patients using IUD as contraceptive method (n= 562 cases) were included in the study. The samples taken with the conventional method were excluded from the study. The results were categorized according to the Bethesda system. The age range of the patients was 18-61 years (mean age: 34.6). The most common diagnosis was "negative for intraepithelial lesion or malignancy" (97.2%). In 307 patients (54.6%) there were infection and only in 93 out of them (30.2%) a specific agent was detected. Actinomyces (11%) were recorded as the most common infectious agent, followed by Gardnerella vaginalis (2.8%) and Candida species (2.4%). There were reactive changes in 134 cases (23.8%). In 13 cases (2.3%) epithelial cell abnormalities were detected. The most common cytopathologic diagnosis was ASC-US (atypical squamous cells of undetermined significance) in patients who had epithelial cell abnormalities (2.1%). In conclusion, IUDs increase the frequency of genital infection by disrupting the genital flora. In our study the most frequent agent was Actinomyces, and this rate was higher than some studies. This high rate for Actinomyces may be associated with IUDs that are frequently used for contraception in Erzurum province with long term uses. (Afr J Reprod Health 2022; 26[1]: 47-52). Keywords: IUD, cervico-vaginal smear, liquid based cytology, PAP test Le dispositif intra-uterin (DIU), est l'une des methodes de contraception les plus efficaces. Le but de l'etude est d'etudier les effets du dispositif intra-uterin dans les frottis cervico-vaginaux avec une technique de cytologie a base de liquide dans notre population de patients. Les frottis cervico-vaginaux de 5492 patientes qui ont sollicite les services du service de pathologie au cours d'une periode de six mois ont ete revus retrospectivement. Les echantillons ont ete prepares avec une technique de cytologie a base de liquide. Les patientes utilisant le DIU comme methode contraceptive (n= 562 cas) ont ete incluses dans l'etude. Les echantillons preleves avec la methode conventionne