Volumetry after botulinum toxin A: the impact on abdominal wall compliance and endotracheal pressure

Purpose Botulinum toxin type A (BTA) is an adjuvant tool used in the preoperative optimization of complex hernias before abdominal wall reconstruction (AWR). This study aims to investigate changes in the abdominal cavity and hernia sac dimensions after BTA application. Method A prospective study with 27 patients with a hernia defect of ≥ 10 cm and loss of domain (LOD) ≥ 20% underwent AWR. Computed tomography (CT) measurements and volumetry before and after the application of BTA were performed. Intraoperative and postoperative outcomes were evaluated. Results Imaging post-BTA revealed hernia width reduction of 1.9 cm ( p = 0.002), lateral abdominal wall muscle elongation of 3.1 cm ( p