Bubble Deformation Analysis Near Curved Elastic Wall for Developing Shock Wave DDS (2nd Report, Effect of Gas of Bubble and Curved Elastic Wall)

This paper describes fundamental investigation to apply penetration of micro jet to disintegrate microcapsules in Drug Delivery System (DDS). Deformation processes of a bubble near curved elastic wall by shock wave were observed by optical shadowgraph method using a high-speed camera. It is found that a bubble generates micro jet toward a wall and opposite side whose characteristics are affected by gas of bubble, position of an initial bubble, wall elasticity, and wall curvature. Therefore, changing them about microcapsule can control penetration force by micro jet.