Myogenically differentiated mesenchymal stem cell insulin sensitivity is associated with infant adiposity at 1 and 6 months of age

Myogenically differentiated mesenchymal stem cell insulin sensitivity is associated with infant adiposity at 1 and 6 months of age

Objective In adults, skeletal muscle insulin sensitivity (SI) and fatty acid oxidation (FAO) are linked with a predisposition to obesity. The current study aimed to determine the effects of maternal exercise on a model of infant skeletal muscle tissue (differentiated umbilical cord mesenchymal stem...

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Veröffentlicht in:Obesity (Silver Spring, Md.) Md.), 2023-09, Vol.31 (9), p.2349-2358
Hauptverfasser: Jevtovic, Filip, Zheng, Donghai, Houmard, Joseph A., Kern, Kara, Claiborne, Alex, Lopez, Christian A., Broskey, Nicholas T., Isler, Christy, DeVente, Jim, Newton, Edward, May, Linda E.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Babies
Body fat
Body mass index
Diabetes
Electronic health records
Exercise
Fatty acids
Glucose
Insulin resistance
Metabolism
Musculoskeletal system
Obesity
Obstetrics
Oxidation
Pediatrics
Physical fitness
Questionnaires
Stem cells
Umbilical cord
Womens health
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Zusammenfassung:Objective In adults, skeletal muscle insulin sensitivity (SI) and fatty acid oxidation (FAO) are linked with a predisposition to obesity. The current study aimed to determine the effects of maternal exercise on a model of infant skeletal muscle tissue (differentiated umbilical cord mesenchymal stem cells [MSCs]) SI and FAO and analyzed for associations with infant body composition. Methods Females
ISSN:1930-7381
1930-739X
DOI:10.1002/oby.23829