Effect of acupressure in nausea and vomiting treatment during pregnancy: A meta-analysis

•The study evaluates the effect of acupressure on patients with nausea and vomiting of pregnancy.•Using ‘pregnancy’, ‘nausea’, ‘vomiting’, and ‘acupressure’ as keywords search eight databases.•Acupressure is a safe, noninvasive, economical, and effective intervention measure for reducing nausea and vomiting during pregnancy. Many women experience nausea and vomiting in early pregnancy. Regardless of the disease severity, it affects the work and life of pregnant women. However, drug treatment may potentially impact the foetus; thus, alternative safe and effective measures are essential. We aimed to evaluate the effect of acupressure, a non-drug treatment for nausea and vomiting, during pregnancy. PubMed, EMBASE, Cochrane, Web of Science, CNKI, CBM, VIP, and Wanfang databases were searched using ‘pregnancy’, ‘nausea’, ‘vomiting’, and ‘acupressure’ as keywords. The search period was from database inception to 30 November 2022. Two researchers independently screened articles, extracted data, and used RevMan 5.4 software for statistical analysis. We included 33 trials and 3 390 patients in this meta-analysis. Acupressure was effective for women with nausea and vomiting during pregnancy (odds ratio (OR)= 4.81, 95% confidence interval (CI) [3.47, 6.68]; p