Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis

Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis

To investigate whether immediate response to inhaled nitric oxide (iNO) therapy is associated with reduced mortality in preterm infants with hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH). A systematic review and meta-analysis of observational studies was conducted to examine th...

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Veröffentlicht in:Early human development 2023-09, Vol.184, p.105841-105841, Article 105841
Hauptverfasser: Baczynski, Michelle, Jasani, Bonny, De Castro, Charmaine, Dani, Carlo, Subhedar, Nimish V., Chandrasekharan, Praveen, Lakshminrusimha, Satyan, McNamara, Patrick J., Bischoff, Adrianne R., Jain, Amish
Format: Artikel
Sprache:eng
Schlagworte:
Inhaled nitric oxide
Mortality
Preterm
Pulmonary hypertension
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Zusammenfassung:To investigate whether immediate response to inhaled nitric oxide (iNO) therapy is associated with reduced mortality in preterm infants with hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH). A systematic review and meta-analysis of observational studies was conducted to examine the association between immediate response (improved oxygenation ≤6 h) compared to non-response, and all-cause mortality among preterm infants
ISSN:0378-3782
1872-6232
DOI:10.1016/j.earlhumdev.2023.105841