A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease

A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease

Cost-effective fluid biomarkers for tau aggregate pathology would improve the diagnostic and prognostic work-up of Alzheimer’s disease and facilitate the discovery of anti-tau therapies. We identified MTBR-tau243 as a specific marker for tau aggregate pathology that could be implemented in clinical...

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Veröffentlicht in:Nature medicine 2023-08, Vol.29 (8), p.1912-1913
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692/53/2421
692/699/375/132/1283
Alzheimer's disease
Biomarkers
Biomedical and Life Sciences
Biomedicine
Brain research
Cancer Research
Clinical medicine
Clinical trials
Cognitive ability
Infectious Diseases
Metabolic Diseases
Molecular Medicine
Neurodegenerative diseases
Neuropathology
Neurosciences
Pathology
Research Briefing
Scientific imaging
Tau protein
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description Cost-effective fluid biomarkers for tau aggregate pathology would improve the diagnostic and prognostic work-up of Alzheimer’s disease and facilitate the discovery of anti-tau therapies. We identified MTBR-tau243 as a specific marker for tau aggregate pathology that could be implemented in clinical practice and trials.
doi_str_mv 10.1038/s41591-023-02468-4
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subjects 692/53/2421
692/699/375/132/1283
Alzheimer's disease
Biomarkers
Biomedical and Life Sciences
Biomedicine
Brain research
Cancer Research
Clinical medicine
Clinical trials
Cognitive ability
Infectious Diseases
Metabolic Diseases
Molecular Medicine
Neurodegenerative diseases
Neuropathology
Neurosciences
Pathology
Research Briefing
Scientific imaging
Tau protein
title A fluid biomarker accurately detects tau aggregate pathology in Alzheimer’s disease
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