Reference Ranges of Ventricular Morphology and Function in Healthy Chinese Adults: A Multicenter 3 T MRI Study

Background Magnetic resonance imaging (MRI) reference ranges for ventricular morphology and function in the Chinese population are lacking. Purpose To establish the MRI reference ranges of left and right ventricular (LV and RV) morphology and function based on a large multicenter cohort. Study Type Prospective. Population One thousand and twelve healthy Chinese Han adults. Field Strength/Sequence Balanced steady‐state free procession cine sequence at 3.0 T. Assessment Biventricular end‐diastolic, end‐systolic, stroke volume, and ejection fraction (EDV, ESV, SV, and EF), LV mass (LVM), end‐diastolic and end‐systolic dimension (LVEDD and LVESD), anteroseptal wall thickness (AS), and posterolateral wall thickness (PL) were measured. Body surface area (BSA) and height were used to index biventricular parameters. Parameters were compared between age groups and sex. Statistical Tests Independent‐samples t‐tests or Mann–Whitney U test to compare mean values between sexes; ANOVA or Kruskal–Wallis test to compare mean values among age groups; linear regression to assess the relationships between cardiac parameters and age (correlation coefficient, r). A P value