Umbilical Cord Blood IgA Levels and Bacterial Profile in Preterm Neonates Born with Maternal Risk Factors for Early-Onset Neonatal Sepsis

Umbilical Cord Blood IgA Levels and Bacterial Profile in Preterm Neonates Born with Maternal Risk Factors for Early-Onset Neonatal Sepsis

Objectives To investigate the IgA levels and bacterial profile in umbilical cord blood (UCB) samples of mothers with risk factors compared to those without risk factors; and to understand the link between UCB culture positivity and neonatal outcomes [early-onset sepsis (EOS) or death within 7 d of l...

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Veröffentlicht in:Indian journal of pediatrics 2024-06, Vol.91 (6), p.541-547
Hauptverfasser: Jain, Ashish, Jain, Kajal, Jhurani, Divashree, Mishra, Asha, Mohapatra, Sarita, Sharma, Akash, Manchanda, Vikas, Sankar, M. Jeeva, Agarwal, Ramesh
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Case-Control Studies
Chorioamnionitis - microbiology
Female
Fetal Blood - microbiology
Gynecology
Humans
Immunoglobulin A - blood
Infant, Newborn
Infant, Premature
Male
Medicine
Medicine & Public Health
Neonatal Sepsis - blood
Neonatal Sepsis - microbiology
Original Article
Pediatrics
Pilot Projects
Pregnancy
Prospective Studies
Risk Factors
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Zusammenfassung:Objectives To investigate the IgA levels and bacterial profile in umbilical cord blood (UCB) samples of mothers with risk factors compared to those without risk factors; and to understand the link between UCB culture positivity and neonatal outcomes [early-onset sepsis (EOS) or death within 7 d of life]. Methods This is a pilot prospective case-control study. Mothers with preterm deliveries (gestational age 
ISSN:0019-5456
0973-7693
DOI:10.1007/s12098-023-04708-4