Application of FT-IR Spectroscopy for Mycobacterium abscessus complex subspecies differentiation

Mycobacterium abscessus complex (MABSC) subspecies differentiation improves patients' therapy and outcome. Fourier-Transform-Infrared Spectroscopy (FT-IRS) was applied for subspecies discrimination of 15 strains on different media: Löwenstein-Jensen showed the best resolution power; Linear Disc...

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Veröffentlicht in:	Journal of microbiological methods 2023-09, Vol.212, p.106792-106792, Article 106792
Hauptverfasser:	Curtoni, Antonio, Cordovana, Miriam, Bondi, Alessandro, Scaiola, Francesca, Criscione, Giulia, Ghibaudo, Davide, Pastrone, Lisa, Zanotto, Elisa, Camaggi, Anna, Caroppo, Maria Simona, Kostrzewa, Markus, Cavallo, Rossana, Costa, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	FT-IR spectroscopy IR biotyper LPA Mycobacterium abscessus complex Subtyping
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Mycobacterium abscessus complex (MABSC) subspecies differentiation improves patients' therapy and outcome. Fourier-Transform-Infrared Spectroscopy (FT-IRS) was applied for subspecies discrimination of 15 strains on different media: Löwenstein-Jensen showed the best resolution power; Linear Discriminant Analysis model differentiated M. abscessus susbsp. abscessus from M. abscessus subsp. massiliense. FT-IRS has a potential role in rapidly MABSC subspecies identification. •Discrimination of Mycobacterium abscessus complex subspecies in mandatory to the correct choice of antimicrobial therapy.•The Fourier Transform-Infrared Spectroscopy technology rapidly discriminating between Mycobacterium abscessus complex subspecies.
ISSN:	0167-7012 1872-8359
DOI:	10.1016/j.mimet.2023.106792