The case for BALT in human respiratory immunity

The case for BALT in human respiratory immunity

Bronchus-associated lymphoid tissue (BALT), which develops in the lung during infancy before declining over childhood, supports localized immune reactions against airway infections in early life including the generation of germinal center-like B cells specific for respiratory pathogens.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature immunology 2023-08, Vol.24 (8), p.1220-1221
Hauptverfasser: Ding, Zhoujie, Tarlinton, David
Format: Artikel
Sprache:eng
Schlagworte:
631/250/1619
631/250/2152
631/250/347
Age
Antibodies
Antigens
Biomedical and Life Sciences
Biomedicine
Bronchus
Cells
Children
Flow cytometry
Histology
Humans
Immunology
Infections
Infectious Diseases
Lungs
Lymphatic system
Lymphocytes
Lymphocytes B
Lymphoid Tissue
News & Views
news-and-views
Pathogens
Pediatrics
Respiratory diseases
Vaccines
Viruses
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Bronchus-associated lymphoid tissue (BALT), which develops in the lung during infancy before declining over childhood, supports localized immune reactions against airway infections in early life including the generation of germinal center-like B cells specific for respiratory pathogens.
ISSN:1529-2908
1529-2916
DOI:10.1038/s41590-023-01566-2