Multiple cortical lesions with grainy enhancement of magnetic resonance imaging in anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated encephalitis with seizures (FLAMES)

•An adult manifested seizures, headaches and cortical symptoms compatible with FLAMES.•Characteristic multiple cortical and subcortical grainy enhancements were observed.•This finding indicates the vasculitic nature of MOGAD and FLAMES.•This finding helps with the diagnosis and understanding pathoge...

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Veröffentlicht in:	Journal of the neurological sciences 2023-08, Vol.451, p.120729-120729, Article 120729
Hauptverfasser:	Takegami, Naoki, Murai, Hiroyuki, Mori, Harushi, Yamaguchi-Takegami, Nanaka, Toda, Tatsushi, Iwata, Nobue K., Goto, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-myelin oligodendrocyte glycoprotein antibody Autoantibodies Blood–brain barrier Encephalitis - complications Encephalitis - diagnostic imaging Epilepsy FLAMES Humans Magnetic Resonance Imaging MOG Myelin-Oligodendrocyte Glycoprotein Oligodendroglia Seizures - complications Seizures - etiology Vasculitis
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Beschreibung
Zusammenfassung:	•An adult manifested seizures, headaches and cortical symptoms compatible with FLAMES.•Characteristic multiple cortical and subcortical grainy enhancements were observed.•This finding indicates the vasculitic nature of MOGAD and FLAMES.•This finding helps with the diagnosis and understanding pathogenesis of this disorder.
ISSN:	0022-510X 1878-5883
DOI:	10.1016/j.jns.2023.120729