Microarrays of Peptide Fibrils Created by Electrostatically Controlled Deposition

Microarrays of Peptide Fibrils Created by Electrostatically Controlled Deposition

The adsorption of β‐sheet‐rich fibrils produced in vitro via the self‐assembly of polypeptides onto surfaces is found to be governed by electrostatic interactions. Chemically patterned substrates are used to create lateral micropatterns of fibrils and hybrid microstructures of fibrils with inorganic...

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Veröffentlicht in:Advanced materials (Weinheim) 2005-04, Vol.17 (7), p.893-897
Hauptverfasser: Mesquida, P., Ammann, D. L., MacPhee, C. E., McKendry, R. A.
Format: Artikel
Sprache:eng
Schlagworte:
Fibrils
micro
Patterning
Patterning, micro
Peptides
Self-assembly
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Zusammenfassung:The adsorption of β‐sheet‐rich fibrils produced in vitro via the self‐assembly of polypeptides onto surfaces is found to be governed by electrostatic interactions. Chemically patterned substrates are used to create lateral micropatterns of fibrils and hybrid microstructures of fibrils with inorganic nanoparticles (see Figure). β‐sheet‐rich fibrils are promising as functional biomaterials.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200401229