Regulatory T cells aid stem-cell therapy for Parkinson’s disease

Regulatory T cells aid stem-cell therapy for Parkinson’s disease

Inflammation caused by surgical trauma limits the survival of transplanted stem-cell-derived neurons in rodent models of Parkinson’s disease. Co-transplanting immune cells called regulatory T cells improves the therapy’s efficacy. Regulatory T cells dampen inflammation associated with surgery.

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Veröffentlicht in:Nature (London) 2023-07, Vol.619 (7970), p.470-472
1. Verfasser: Tang, Qizhi
Format: Artikel
Sprache:eng
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Humanities and Social Sciences
multidisciplinary
News And Views
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Zusammenfassung:Inflammation caused by surgical trauma limits the survival of transplanted stem-cell-derived neurons in rodent models of Parkinson’s disease. Co-transplanting immune cells called regulatory T cells improves the therapy’s efficacy. Regulatory T cells dampen inflammation associated with surgery.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-023-02177-5