A high-resolution SPECT system based on a microchannel-plate imager

The authors have developed a high-resolution single-photon emission computed tomography (SPECT) system for small-animal studies with /sup 125/I. The SPECT camera uses a Hamamatsu microchannel-plate imager PIAS (photon-counting image acquisition system), a 0.7-mm-thick NaI(Tl) plate, and a lead-glass...

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Veröffentlicht in:	IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (USA) 1990-04, Vol.37 (2), p.687-695
Hauptverfasser:	Dilmanian, F.A., Weber, D.A., Coderre, J.A., Joel, D.D., Shi, K.-C., Meinken, G.E., Som, P., Tang, Y.-N., Volkow, N.D., Yee, C., Brill, A.B., Watanabe, M., Inuzuka, E., Oba, K., Gerson, R., Iida, H., Hiruma, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	07 ISOTOPES AND RADIATION SOURCES 550601 > Medicine-- Unsealed Radionuclides in Diagnostics 655002 > Medical Physics-- Radiation Source Calibration & Standardization 655003 > Medical Physics-- Dosimetry BETA DECAY RADIOISOTOPES CAMERAS COLLIMATORS Computed tomography COMPUTERIZED TOMOGRAPHY DAYS LIVING RADIOISOTOPES DESIGN DIAGNOSTIC TECHNIQUES ELECTRON CAPTURE RADIOISOTOPES ELEMENTS EMISSION COMPUTED TOMOGRAPHY Face detection FIBERS GAMMA CAMERAS Gamma ray detection Gamma ray detectors IMAGE PROCESSING Image reconstruction Image resolution IMAGE SCANNERS INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY INTERMEDIATE MASS NUCLEI IODINE 125 IODINE ISOTOPES ISOTOPES LEAD MEASURING INSTRUMENTS METALS MOCKUP NAI DETECTORS NUCLEI ODD-EVEN NUCLEI Optical collimators OPTICAL FIBERS PHANTOMS PROCESSING RADIATION DETECTORS RADIATION PROTECTION AND DOSIMETRY RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE SCINTILLATION COUNTERS SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY SOLID SCINTILLATION DETECTORS STRUCTURAL MODELS TOMOGRAPHY 440103 > Radiation Instrumentation-- Nuclear Spectroscopic Instrumentation
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Zusammenfassung:	The authors have developed a high-resolution single-photon emission computed tomography (SPECT) system for small-animal studies with /sup 125/I. The SPECT camera uses a Hamamatsu microchannel-plate imager PIAS (photon-counting image acquisition system), a 0.7-mm-thick NaI(Tl) plate, and a lead-glass parallel-hole collimator. The 15-mm-diameter field of view (FOV) of the PIAS tube was enlarged by an optical fiber faceplate taper to provide a 26-mm camera FOV. Camera absolute sensitivity (counts detected/gamma photons emitted) is 2*10/sup -5/ for /sup 125/I. The system provides an in-plane resolution of about 0.7 mm FWHM (full width at half maximum) in the reconstructed image for a 15-mm radius of rotation. SPECT images from phantom studies and from organs in the rat and mouse provide examples of the resolving capacity of the system.< >
ISSN:	0018-9499 1558-1578
DOI:	10.1109/23.106699