Right ventricular to pulmonary artery coupling and outcome in patients with cardiac amyloidosis

Right ventricular to pulmonary artery coupling and outcome in patients with cardiac amyloidosis

Abstract Aims To investigate the prognostic value of the right ventricle-to-pulmonary artery (RV-PA) coupling in patients with either transthyretin (ATTR) or immunoglobulin light-chain (AL) cardiac amyloidosis (CA). Methods and results Overall, 283 patients with CA from 3 Italian high-volume centres...

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Veröffentlicht in:European heart journal cardiovascular imaging 2023-09, Vol.24 (10), p.1405-1414
Hauptverfasser: Tomasoni, Daniela, Adamo, Marianna, Porcari, Aldostefano, Aimo, Alberto, Bonfioli, Giovanni Battista, Castiglione, Vincenzo, Franzini, Maria, Inciardi, Riccardo Maria, Khalil, Anas, Lombardi, Carlo Mario, Lupi, Laura, Nardi, Matilde, Oriecuia, Chiara, Pagnesi, Matteo, Panichella, Giorgia, Rossi, Maddalena, Saccani, Nicola, Specchia, Claudia, Vergaro, Giuseppe, Merlo, Marco, Sinagra, Gianfranco, Emdin, Michele, Metra, Marco
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Sprache:eng
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Zusammenfassung:Abstract Aims To investigate the prognostic value of the right ventricle-to-pulmonary artery (RV-PA) coupling in patients with either transthyretin (ATTR) or immunoglobulin light-chain (AL) cardiac amyloidosis (CA). Methods and results Overall, 283 patients with CA from 3 Italian high-volume centres were included (median age 76 years; 63% males; 53% with ATTR-CA, 47% with AL-CA). The RV-PA coupling was evaluated by using the tricuspid annular plane systolic excursion/pulmonary artery systolic pressure (TAPSE/PASP) ratio. The median value of TAPSE/PASP was 0.45 (0.33–0.63) mm/mmHg. Patients with a TAPSE/PASP ratio
ISSN:2047-2404
2047-2412
DOI:10.1093/ehjci/jead145