Local cytokine levels associate with SNOT‐22 and UPSIT scores in chronic rhinosinusitis

Local cytokine levels associate with SNOT‐22 and UPSIT scores in chronic rhinosinusitis

Key points Elevated IL‐5, IL‐13, IL‐33, and CCL2 correlate with lower UPSIT scores in CRS and AERD patients. Elevated IL‐5, IL‐13, TNF‐α, CCL2, and CXCL‐8 correlate with higher SNOT‐22 scores in CRS and AERD patients.

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Veröffentlicht in:International forum of allergy & rhinology 2024-01, Vol.14 (1), p.114-118
Hauptverfasser: Yu, Sophie E., Chiang, Simon, Olonisakin, Tolani F., Moore, John A., Bergmark, Regan W., Maxfield, Alice Z., Roditi, Rachel E., Buchheit, Kathleen M., Lundberg, Marie, Mitchell, Margaret B., Lee, Stella E.
Format: Artikel
Sprache:eng
Schlagworte:
22‐item Sino‐Nasal Outcome Test (SNOT‐22)
Chronic Disease
chronic rhinosinusitis (CRS)
Cytokines
endotype
Humans
Interleukin-13
Interleukin-5
Lund‐Kennedy (LK)
Monocyte chemoattractant protein 1
Nasal Polyps
patient‐reported outcome measures (PROM)
Rhinitis - diagnosis
Rhinosinusitis
Sino-Nasal Outcome Test
Sinusitis - diagnosis
University of Pennsylvania Smell Identification Test (UPSIT)
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Zusammenfassung:Key points Elevated IL‐5, IL‐13, IL‐33, and CCL2 correlate with lower UPSIT scores in CRS and AERD patients. Elevated IL‐5, IL‐13, TNF‐α, CCL2, and CXCL‐8 correlate with higher SNOT‐22 scores in CRS and AERD patients.
ISSN:2042-6976
2042-6984
DOI:10.1002/alr.23222