Neuropsychological Correlates of Adherence in Youth with Behaviorally Acquired HIV

Neuropsychological Correlates of Adherence in Youth with Behaviorally Acquired HIV

Youth living with behaviorally acquired HIV (YLWH) are at-risk for both neuropsychological disorders and antiretroviral therapy (ART) non-adherence; little is known about their interrelationship over time in YLWH. Neuropsychological and psychiatric functioning, substance use, and self-report of 7-da...

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Veröffentlicht in:AIDS and behavior 2023-11, Vol.27 (11), p.3813-3829
Hauptverfasser: Garvie, Patricia A., Loop, Matthew S., Zhou, Christina W., McCumber, Micah, Woods, Steven Paul, Nichols, Sharon L.
Format: Artikel
Sprache:eng
Schlagworte:
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Bayesian analysis
CD4 antigen
Drug abuse
Executive function
Health Psychology
HIV
Human immunodeficiency virus
Infectious Diseases
Longitudinal studies
Mathematical models
Medicine
Medicine & Public Health
Neuropsychology
Original Paper
Patient compliance
Public Health
Substance abuse
Substance use
Teenagers
Young adults
Youth
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Zusammenfassung:Youth living with behaviorally acquired HIV (YLWH) are at-risk for both neuropsychological disorders and antiretroviral therapy (ART) non-adherence; little is known about their interrelationship over time in YLWH. Neuropsychological and psychiatric functioning, substance use, and self-report of 7-day/week and weekend ART adherence were assessed at baseline and Weeks 24, 48, 96 and 144 of a longitudinal study evaluating the impact of early (CD4>350) versus standard of care (CD4≤350) treatment initiation on neuropsychological functioning in 111 treatment-naïve YLWH age 18–24 years at entry. Bayesian multi-level models for adherence ( ≥  90% vs.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-023-04096-y