Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg

Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg

Approximately 40% of people with hypertension have left ventricular hypertrophy (LVH) detected by ECG or echocardiography. Because patients with LVH have poor myocardial microcirculation, they may be too sensitive to lowering systolic blood pressure (SBP) too much due to a lack of myocardial perfusi...

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Veröffentlicht in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2023-08, Vol.80 (8), p.1739-1748
Hauptverfasser: Heimark, Sondre, Mehlum, Maria H., Mancia, Giuseppe, Søraas, Camilla L., Liestøl, Knut, Wachtell, Kristian, Larstorp, Anne C., Rostrup, Morten, Mariampillai, Julian E., Kjeldsen, Sverre E., Julius, Stevo, Weber, Michael A.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Antihypertensive Agents - pharmacology
Antihypertensive Agents - therapeutic use
Blood Pressure
Electrocardiography
Humans
Hypertension
Hypertrophy, Left Ventricular - complications
Hypertrophy, Left Ventricular - diagnostic imaging
Hypertrophy, Left Ventricular - drug therapy
Middle Aged
Valsartan - pharmacology
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Zusammenfassung:Approximately 40% of people with hypertension have left ventricular hypertrophy (LVH) detected by ECG or echocardiography. Because patients with LVH have poor myocardial microcirculation, they may be too sensitive to lowering systolic blood pressure (SBP) too much due to a lack of myocardial perfusion pressure. We aimed to investigate whether the average achieved SBP
ISSN:0194-911X
1524-4563
DOI:10.1161/HYPERTENSIONAHA.123.21454