Research progress on the role of PDGF/PDGFR in type 2 diabetes

Platelet-derived growth factors (PDGFs) are basic proteins stored in the α granules of platelets. PDGFs and their receptors (PDGFRs) are widely expressed in platelets, fibroblasts, vascular endothelial cells, platelets, pericytes, smooth muscle cells and tumor cells. The activation of PDGFR plays a...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2023-08, Vol.164, p.114983-114983, Article 114983
Hauptverfasser:	Cao, Zhanqi, Liu, Yijie, Wang, Yini, Leng, Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerotic Diabetes complications Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetic Nephropathies - metabolism Endothelial Cells - metabolism Female Humans PDGF PDGFR Platelet-Derived Growth Factor - metabolism Pregnancy Receptor, Platelet-Derived Growth Factor beta - metabolism Receptors, Platelet-Derived Growth Factor - metabolism Retinopathy
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