Directionally controlling flavor compound profile based on the structure of synthetic microbial community in Chinese liquor fermentation

Most traditional fermented foods are produced by spontaneous fermentation. It is difficult to produce traditional fermented foods with desired flavor compound profile. In this study, using Chinese liquor fermentation as a case, we aimed to directionally control flavor compound profile in food fermentation. Twenty key flavor compounds were identified in 80 Chinese liquor fermentations. Six microbial strains, identified as high producers of these key flavor compounds, were used to generate the minimal synthetic microbial community. A mathematical model was established to link the structure of the minimal synthetic microbial community and the profile of these key flavor compounds. This model could generate the optimal structure of synthetic microbial community to produce flavor compounds with desired profile. This work provided a strategy to realize the directional control of flavor compound profile via controlling the structure of the synthetic microbial community in Chinese liquor fermentation. •Twenty key flavor compounds were identified in Chinese liquor fermentation.•A synthetic microbial community was constructed to produce key flavor compounds.•Flavor compound profile was regulated by structure of synthetic microbial community.•A model was used to link synthetic microbial community and flavor compound profile.•The model can be used to control flavor compound profile in liquor fermentation.