Antibody-Associated Reversal of ATTR Amyloidosis–Related Cardiomyopathy

The investigators describe antibodies that bound amyloid in three patients with transthyretin amyloidosis. Spontaneous regression of cardiomyopathy occurred in all three patients.

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Veröffentlicht in:The New England journal of medicine 2023-06, Vol.388 (23), p.2199-2201
Hauptverfasser: Fontana, Marianna, Gilbertson, Janet, Verona, Guglielmo, Riefolo, Mattia, Slamova, Ivana, Leone, Ornella, Rowczenio, Dorota, Botcher, Nicola, Ioannou, Adam, Patel, Rishi K., Razvi, Yousuf, Martinez-Naharro, Ana, Whelan, Carol J., Venneri, Lucia, Duhlin, Amanda, Canetti, Diana, Ellmerich, Stephan, Moon, James C., Kellman, Peter, Al-Shawi, Raya, McCoy, Laura, Simons, J. Paul, Hawkins, Philip N., Gillmore, Julian D.
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Sprache:eng
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Zusammenfassung:The investigators describe antibodies that bound amyloid in three patients with transthyretin amyloidosis. Spontaneous regression of cardiomyopathy occurred in all three patients.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc2304584