Unraveling the genetic mechanisms governing the host response to bovine anaplasmosis

Unraveling the genetic mechanisms governing the host response to bovine anaplasmosis

•The transcriptional landscape of blood PBMCs of Anaplasma marginale infected cattle was compared with healthy controls.•A total of 676 up-regulated and 323 down-regulated genes were observed in the infected animals (Fold change >2, FDR 

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Veröffentlicht in:Gene 2023-08, Vol.877, p.147532-147532, Article 147532
Hauptverfasser: Ahlawat, Sonika, Choudhary, Vikas, Kaur, Rashmeet, Arora, Reena, Sharma, Rekha, Chhabra, Pooja, Kumar, Ashish, Kaur, Mandeep
Format: Artikel
Sprache:eng
Schlagworte:
Anaplasma marginale - genetics
Anaplasmosis
Anaplasmosis - epidemiology
Anaplasmosis - genetics
Animals
Cattle
Cattle Diseases - genetics
Cytokines
Gene expression
Leukocytes, Mononuclear
PBMCs
Signal Transduction - genetics
Transcriptome
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Beschreibung
Zusammenfassung:•The transcriptional landscape of blood PBMCs of Anaplasma marginale infected cattle was compared with healthy controls.•A total of 676 up-regulated and 323 down-regulated genes were observed in the infected animals (Fold change >2, FDR 
ISSN:0378-1119
1879-0038
DOI:10.1016/j.gene.2023.147532