Unexplained fetal death, pre-eclampsia and fetal growth restriction in pregnancy: Who is screened for antiphospholipid syndrome?

Unexplained fetal death, pre-eclampsia and fetal growth restriction in pregnancy: Who is screened for antiphospholipid syndrome?

•Unexplained fetal death, pre-eclampsia and fetal growth restriction may be the heralding manifestation of APS•The diagnosis obstetric APS is important to prevent further APS-related morbidity•Testing for aPL in women with late pregnancy morbidity is rarely performed in real life•aPL autoantibodies...

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Veröffentlicht in:Thrombosis research 2023-08, Vol.228, p.61-63
Hauptverfasser: Gros, Clothilde, Barral, Tiphaine, Mageau, Arthur, Roland Nicaise, Pascale, Vivier, Valérie, Papo, Thomas, Bourgeois-Moine, Agnès, Goulenok, Tiphaine, Sacre, Karim
Format: Artikel
Sprache:eng
Schlagworte:
Antiphospholipid autoantibodies
Obstetric antiphospholipid syndrome
Pregnancy
Screening
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Beschreibung
Zusammenfassung:•Unexplained fetal death, pre-eclampsia and fetal growth restriction may be the heralding manifestation of APS•The diagnosis obstetric APS is important to prevent further APS-related morbidity•Testing for aPL in women with late pregnancy morbidity is rarely performed in real life•aPL autoantibodies are positive in almost 15% of cases when searched in such setting
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2023.05.014