Impact of Lipoprotein (a) on Long-Term Outcomes in Patients With Acute Myocardial Infarction

Background: Lipoprotein (a) (Lp(a)) is a complex circulating lipoprotein, and there is increasing evidence it is a risk factor for atherosclerotic cardiovascular disease (ASCVD). This study aimed to investigate the influence of Lp(a) serum levels on long-term outcomes after acute myocardial infarcti...

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Veröffentlicht in:	Circulation Journal 2023/06/01, pp.CJ-23-0221
Hauptverfasser:	Dai, Kazuoki, Shiode, Nobuo, Yoshii, Kanade, Kimura, Yuka, Matsuo, Keita, Jyuri, Yusuke, Tomomori, Shunsuke, Higaki, Tadanao, Oi, Kuniomi, Kawase, Tomoharu, Sairaku, Akinori, Ohashi, Norihiko, Suenari, Kazuyoshi, Nishioka, Kenji, Masaoka, Yoshiko, Nakano, Yukiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myocardial infarction Humans Lipoprotein(a) Lipoproteins Myocardial Infarction - epidemiology Outcomes Proportional Hazards Models Risk Assessment Risk Factors
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Zusammenfassung:	Background: Lipoprotein (a) (Lp(a)) is a complex circulating lipoprotein, and there is increasing evidence it is a risk factor for atherosclerotic cardiovascular disease (ASCVD). This study aimed to investigate the influence of Lp(a) serum levels on long-term outcomes after acute myocardial infarction (AMI).Methods and Results: Between January 2015 and January 2018, we enrolled 262 patients with AMI who underwent coronary angiography within 24 h of the onset of chest pain and had available Lp(a) data enabling subdivision into 2 groups: high Lp(a) (≥32 mg/dL: n=76) and low Lp(a) (
ISSN:	1346-9843 1347-4820 1347-4820
DOI:	10.1253/circj.CJ-23-0221