Blood Loss in Operation Is Independently Predictive of Postoperative Ventriculoperitoneal Shunt in Pediatric Patients With Posterior Fossa Tumors

To identify the risk factors for postoperative hydrocephalus and the need for ventriculoperitoneal (VP) shunt after posterior fossa tumor (PFT) resection in pediatric patients and establish a predictive model. A total of 217 pediatric patients (≤14 years old) with PFTs who underwent tumor resection...

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Veröffentlicht in:Pediatric neurology 2023-07, Vol.144, p.119-125
Hauptverfasser: Hu, Sheng-Qi, Guo, Zhong-Yin, Wan, Li-Jun, Chen, Zi-Rong, Wan, Feng
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Sprache:eng
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Zusammenfassung:To identify the risk factors for postoperative hydrocephalus and the need for ventriculoperitoneal (VP) shunt after posterior fossa tumor (PFT) resection in pediatric patients and establish a predictive model. A total of 217 pediatric patients (≤14 years old) with PFTs who underwent tumor resection from November 2010 to December 2020 were divided into a VP shunt group (n = 29) and non-VP shunt group (n = 188). Univariate and multivariate logistic regression were performed. A predictive model was established based on the independent predictors. Receiver operating characteristic curves were generated to determine the cutoff values and areas under the curve (AUCs). The Delong test was performed to compare the AUCs. Age less than three years (P = 0.015, odds ratio [OR] = 3.760), blood loss (BL) (P = 0.002, OR = 1.601), and locations at fourth ventricle (P 
ISSN:0887-8994
1873-5150
DOI:10.1016/j.pediatrneurol.2023.04.023