Flexible information representation to stabilize sensory perception despite minor external input variations

Sensory information about the environment constantly changes or varies depending on circumstances. However, once we repeatedly experience objects, our brain can perceive and recognize them as identical, even if they are slightly altered or include some diversity. We can stably perceive things without interference from minor external changes or variety. Our recent study focusing on visual perception showed that repeatedly viewing the same oriented grating stimuli enables information representation for low-contrast (or weak-intensity) orientations in the primary visual cortex. We observed low contrast–preferring neurons, whose firing rates increased by reducing the luminance contrast. The number of such neurons increased after the experience, and the neuronal population, including such neurons, can represent even low-contrast orientations. This study indicated that experience leads to flexible information representations that continuously respond to inputs of various strengths at the neuronal population level in the primary sensory cortex. In this perspective article, in addition to the above mechanism, I would discuss alternative mechanisms for perceptual stabilization. The primary sensory cortex represents external information faithfully without alterations, as well as in a state distorted by experience. Both sensory representations may cooperatively and dynamically affect hierarchical downstream, resulting in stable perception. •Repeated experience increases the proportion of V1 neurons responding strongly at low contrast.•Low contrast–preferring neurons contribute to visual perception when images become indistinct.•A change in the excitation-inhibition balance may generate low-contrast preference in V1.•Flexible information representation can adapt input diversity in the discrimination axis.•Sensory information can be stably perceived even with fluctuations in both inputs and responses.